Heart Failure in the Child and Young Adult

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Heart Failure in the Child and Young Adult,

Edition 1 From Bench to Bedside

Editors: Edited by Joseph Rossano, M.D., M.S., John Lynn Jefferies, Anthony C Chang, MD, MBA, MPH, Jeffrey A. Towbin, MD and Robert E Shaddy, MD

Publication Date: 05 Dec 2017

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Heart Failure in the Child and Young Adult: From Bench to Bedside combines multiple etiologies for pediatric heart failure, including congenital heart disease, cardiomyopathies, infectious diseases and metabolic abnormalities. This comprehensive resource combines research from multiple contributors with current guidelines to bridge the knowledge gap for the recognition and management of heart failure in children. Coverage begins with the basic science of heart failure, then progresses through diagnosis, management, treatment and surgery, finally concluding with advanced special topics, including genetics, self-management and nanomedicine.

Key Features

Provides coverage of the basic science of heart failure, its epidemiology and economic aspects, outpatient and inpatient management, and advanced therapies, including mechanical circulatory support and heart transplantation
Combines cutting-edge research with current guidelines from the field

About the author

Edited by Joseph Rossano, M.D., M.S., Executive Director, The Cardiac Center, Medical Director, Heart Failure and Transplantation, Associate Professor of Pediatrics, The Children’s Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, USA; John Lynn Jefferies, Cincinnati Children’s Hospital, OH, USA; Anthony C Chang, MD, MBA, MPH, Chief Intelligence and Innovation Officer, Medical Director, The Sharon Disney Lund Medical Intelligence and Innovation Institute (MI3), Children's Hospital of Orange County, USA ; Jeffrey A. Towbin, MD, Cincinnati Children’s Hospital, OH, USA and Robert E Shaddy, MD, Chief of the Division of Cardiology, Jennifer Terker Endowed Chair in Pediatric Cardiology at CHOP

Section I: Basic Science of Heart Failure

1. Molecular and Cellular Mechanisms in Heart Failure

Luisa Mestroni

2. Cardiovascular Receptors and Signaling in Heart Failure

Daniel Bernstein

3. Inflammatory Mediators in Heart Failure

Kory Lavine and Douglas L. Mann

4. Mechanisms of Hypertrophy in Heart Failure

Bernhard Kuhn, Shawn Clark West and Matthew Zinn

5. Hemodynamic Adaptive Mechanisms in Heart Failure

Alexander Hussey, Robert Gideon Weintraub and Lucas Eastaugh

6. Neurohormonal Axis and Natriuretic Peptides in Heart Failure

Melanie Everitt and Stephanie Jialing Nakano

7. The Pressure-Volume Relationship in Heart Failure

Dan Penny

8. Systolic and Diastolic Dysfunction Mechanisms and Assessment of Systolic vs Diastolic Heart Failure

Antonio Gabriel Cabrera

9. The Alveolar-Capillary Interface and Pulmonary Edema

David Wessel

10. Echocardiographic Quantitation of Ventricular Function

Mark Friedberg

11. Magnetic Resonance Imaging Assessment of Heart Failure

Michael Taylor

12. Assessment of Heart Failure by Invasive Methods

Jonathan Jack Rome and Michael Liam O'Byrne

Section II: Clinical Diagnosis and Management of Pediatric Heart Failure

13. Epidemiology and Economic Aspects of Pediatric Heart Failure

Joseph William Rossano

14. Clinical Recognition of Congestive Heart Failure in Children

David Driscoll and Jonathan N. Johnson

15. Classification of Heart Failure

Robert D. Ross

16. Right Ventricular Dysfunction

Andrew Redington

17. Pediatric Myocarditis

Charles Canter and Kathleen Simpson

18. Dilated Cardiomyopathy

Kimberly Lin, Shelley Miyamoto and Kurt Schumacher

19. Clinical Features of Restrictive Cardiomyopathy and Constrictive Pericarditis

Sue Denfield

20. Hypertrophic Cardiomyopathy

Steven D. Colan

21. Left Ventricular Noncompaction

Jeffrey A. Towbin

22. Arrhythmogenic Cardiomyopathies

Frank Marcus and Julia Indik

23. Valvular Insufficiency and Heart Failure

Matthew Schwartz, Andrew C. Glatz and Matthew J. Gillespie

24. Valvular Stenosis and Heart Failure

Anne Dipchand and Emilie Jean-St-Michel

25. Coronary Artery Disease in Children and Young Adults

James C. Fang and Weining David Xu

26. Heart Failure in Congenital Heart Disease Including Single Ventricle Circulation

David Rosenthal

27. Heart Failure in Adults With Congenital Heart Disease

Alexander Opotowsky, Heather Ross and Luke Burchill

28. Dysrhythmias and Ventricular Dysfunction and Heart Failure

Maully Shah and Jeffrey Kim

29. Heart Failure in the Fetus

Edgar Jaeggi and Mary T. Donofrio

30. Heart Failure in the Neonate

Matthew J. O'Connor, Thomas Daniel Ryan and Steven James Kindel

31. Heart Failure in Pediatric Pulmonary Diseases

Dunbar Ivy

32. Heart Failure and the Pediatric Cardiorenal Syndrome

Ahmad Kaddourah and Stuart L. Goldstein

33. Heart Failure in Pediatric Oncologic Disease

Steven Lipshultz, Vivian Isabel Franco, Neha Bansal and Jyothsna Akam Venkata

34. The Failing Cardiovascular System in Sepsis

Maryam Yasmin Naim

35. Outpatient Management of Pediatric Heart Failure

Paul Kantor

36. Quality of Life and Psychosocial Care in Pediatric Heart Failure

Ivan Wilmot and Bradley S. Marino

37. Quality Metrics and Quality Improvement in Pediatric Heart Failure

Jeffrey Anderson

38. Nursing Aspects of Heart Failure

Christine Benhase and Karen Hendricks

Section III: Medical Treatment for Pediatric Heart Failure

39. Diuretics and Invasive Fluid Management Strategies

Jack Price

40. Inotropic Agents in Heart Failure

Steven Schwartz

41. Phosphodiesterase Inhibitors

Timothy Michael Hoffman

42. Use of Vasodilators in Heart Failure

Michael Burch, Jacob Simmonds and Timothy Thiruchelvam

43. Beta-adrenergic Receptor Blockade

Robert Shaddy

44. Low Cardiac Output Syndrome in the Intensive Care Setting

David Nelson

45. New Therapeutic Strategies in Heart Failure

Joseph William Rossano and John Lynn Jefferies

46. Electrophysiologic Devices in Heart Failure

Bryan Cannon

47. Catheter Device Therapy for Heart Failure

Frank Ing

Section IV: Cardiac Surgery and Pediatric Heart Failure

48. Post-Transplant Heart Failure

Elfriede Pahl, Philip Thrush and Simon Urschel

49. Surgical Strategies for the Failing Systemic Ventricle

James Tweddell

50. Valve Intervention for Valve Failure

Ziyad Hijazi, Hussam Suradi and Ralf Holzer

51. General Principles of Mechanical Cardiopulmonary Support

Angela Lorts, Peter Weardon, Jennifer Conway and Timothy Maul

52. Short-Term Mechanical Cardiopulmonary Support Devices

David Luis Simon Morales and Ryan Robert Davies

53. Decision Making in Ventricular Assist Device Support in Pediatric Patients

Elizabeth D. Blume and Christina VanderPluym

54. Long Term Ventricular Assist Devices in Children

Iki c. Adachi, Sarah Burki and Charles Fraser

55. The Adult Experience with Long-Term Assist Devices

William E. Cohn

56. Future of Mechanical Support Devices in Children and Young Adults

Robert Jaquiss

Section V: Special Topics

57. Genetics and Genomics

Michael J. Ackerman and Johan Martijn Bos

58. Genetic Testing

Ray Hershberger

59. Data Management and Analytics

Anthony Chang

60. Self Management and Outpatient Monitoring

John Lynn Jefferies, Anthony Chang, Jacob Mathew and Jennifer Lail

61. Regenerative Medicine and Nanomedicine

James Willerson

62. Nanomedicine

Kevin Maher

63. Nutritonal Assessment and Mangement in Pediatric Heart Failure

Chitra Ravishankar

ISBN: 9780128023938

Page Count: 824

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