The Organic Chemistry of Drug Design and Drug Action,
Edition 4Editors: By Richard B. Silverman, Ph.D Organic Chemistry, Jose I Juncosa and Fengtian Xue
Conformance
-
PDF/UA-1
-
The publication contains a conformance statement that it meets the EPUB Accessibility 1.1, WCAG 2.1, Level AA standard. Please see https://bornaccessible.benetech.org/certified-publishers/ for further details of our compatibility testing.
-
The publication was certified on 20250728
-
Accessibility addendum
-
The certifier's credential is https://bornaccessible.benetech.org/certified-publishers/
-
For detailed accessibility information, see Elsevier’s website at https://www.elsevier.com/about/accessibility
-
Compatibility tested
-
For queries regarding accessibility information, contact [email protected]
Ways Of Reading
-
This e-publication is accessible to the full extent that the file format and types of content allow, on a specific reading device, by default, without necessarily including any additions such as textual descriptions of images or enhanced navigation.
-
All contents of the digital publication necessary to use and understanding, including any text, images (via alternative descriptions), video (via audio description) is fully accessible via suitable audio reproduction.
Navigation
-
The contents of the PDF have been tagged to permit access by assistive technologies as per PDF-UA-1 standard.
-
Page breaks included from the original print source
Additional Accessibility Information
-
All (or substantially all) textual matter is arranged in a single logical reading order (including text that is visually presented as separate from the main text flow, e.g., in boxouts, captions, tables, footnotes, endnotes, citations, etc.). Non-textual content is also linked from within this logical reading order. (Purely decorative non-text content can be ignored).
-
The language of the text has been specified (e.g., via the HTML or XML lang attribute) to optimise text-to-speech (and other alternative renderings), both at the whole document level and, where appropriate, for individual words, phrases or passages in a different language.
-
For readers with color vision deficiency, use of color (e.g., in diagrams, graphics and charts, in prompts, or on buttons inviting a response) is not the sole means of graphical distinction or of conveying information
-
Content is enhanced with ARIA roles to optimize organization and facilitate navigation
-
Where interactive content is included in the product, controls are provided (e.g., for speed, pause and resume, reset) and labelled to make their use clear.
-
WCAG v2.2
Note
-
This product relies on 3rd party tooling which may impact the accessibility features visible in inspection copies. All accessibility features mentioned would be present in the purchased version of the title.
The Organic Chemistry of Drug Design and Drug Action, Fourth Edition presents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action. The book's coverage allows readers to extrapolate core principles and mechanisms to many related classes of drug molecules. It reflects the significant changes in the process of drug design over the last decade and preserves the successful approach of the previous editions while also including significant changes in format and coverage.
It is designed for undergraduate and graduate students in chemistry who are studying medicinal chemistry or pharmaceutical chemistry. Users, including research chemists and biochemists working in pharmaceutical and biotechnology industries will find this update to be useful in their daily work.
Key Features
- Presents new figures that have been extensively updated and refreshed throughout, now in full color
- Provides case studies and up-to-date examples to make the book engaging for today’s student
- Includes new PowerPoint slides with clicker questions and a test bank to enhance the teaching experience
About the author
By Richard B. Silverman, Ph.D Organic Chemistry, Northwestern University, Evanston, IL, USA; Jose I Juncosa, Associate Professor Department of Chemistry Salisbury University, Salisbury, M, USA and Fengtian Xue, Associate Professor of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD, USA
- Introduction
- Lead Discovery
- Lead Modification
- Proteins and Introduction to Receptors
- Drug-Receptor Interactions
- Enzymes
- Enzyme Inhibition and Inactivation
- Nucleic Acids
- Drugs Interacting with Nucleic Acids
- Protein-Protein Interactions: Emerging Drug Targets
- Drug Metabolism
- Drug Resistance and Drug Synergism
- Prodrugs and Drug Delivery Systems
9780198749691; 9781496385024; 9781498702782
Undergraduate and graduate students in chemistry studying medicinal chemistry or pharmaceutical chemistry, Research chemists and biochemists working in pharmaceutical and biotechnology industries