Hematopathology,

Edition 4 A Volume in the Series: Foundations in Diagnostic Pathology

Editors: By Eric D. Hsi, MD, Sa A. Wang, MD and John R. Goldblum, MD, FCAP, FASCP, FACG

Publication Date: 08 Aug 2025

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Part of the popular Foundations in Diagnostic Pathology Series, Hematopathology, Fourth Edition, is a practical and affordable resource that is ideal for study and review as well as everyday clinical practice. With its highly templated format, clearly written text, and concise summary tables, this user-friendly reference helps both trainees and practicing pathologists form accurate diagnoses, avoid pitfalls, and confidently sign out pathology reports on these often difficult and challenging cases.

Key Features

Uses a highly templated format that includes clinical, imaging, and management/prognostic features; pathologic features; ancillary studies; differential diagnosis; and selected bibliography
Focuses on the specific features of various entities, including differential diagnoses
Supplements traditional morphologic diagnostic pathology with clinical, immunohistochemical, and molecular genetic information throughout
Includes new information on the molecular biology of benign and malignant hematologic disorders
Contains numerous quick-reference summary boxes that provide concise and handy key points on the clinical features and pathological features of each disease within hematopathology
Features hundreds of full-color photomicrographs and gross photographs that depict important pathologic features, enabling you to form a differential diagnosis and compare your findings with actual cases
Reflects updated disease classifications according to the 5th edition of World Health Organization (WHO) and The International Consensus Classification (ICC)
Offers contributions from internationally recognized pathologists, keeping you up to date with the latest information in the field
An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date

About the author

By Eric D. Hsi, MD, Professor and Chair, Department of Pathology, Wake Forest School of Medicine, Medical Center Boulevard, USA; Sa A. Wang, MD, Department of Hematopathology, Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, USA; John R. Goldblum, MD, FCAP, FASCP, FACG, Chairman of Pathology, Cleveland Clinic and Professor of Pathology, Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio, USA

SECTION 1 Non-Neoplastic Disorders
1. Red Blood Cell/Hemoglobin Disorders
2. Hemostasis and Thrombosis
3. Nonneoplastic Morphologic Abnormalities of White Blood Cells and Macrophages
4. Reactive Lymph Nodes and Castleman Disease
5. Bone Marrow Failure Syndromes and Germline Disorders With Predisposition to Hematologic Malignancy
6. Benign Causes of Bone Marrow Abnormalities Including Infections, Storage Diseases, Systemic Disorders, and Stromal Changes

SECTION 2 Lymphomas and Mature Lymphoid Leukemias
7. Small B-Cell Lymphomas
8. Diffuse Aggressive B-Cell Lymphomas
9. Peripheral T-Cell Lymphomas
10. Immunodeficiency-Related Lymphoproliferative Disorders
11. Classic Hodgkin Lymphoma
12. Nodular Lymphocyte–Predominant B-Cell Lymphoma
13. B-Cell Leukemias of Mature Lymphocytes
14. Mature T-Cell and Natural Killer–Cell Neoplasms With Leukemic Presentations

SECTION 3 Acute Leukemias and Chronic Myeloid Neoplasms
15. Acute Myeloid Leukemia
16. Precursor Lymphoid Neoplasms
17. Acute Undifferentiated Leukemia and Mixed-Phenotype Acute Leukemias
18. Myeloproliferative Neoplasms, Myelodysplastic/Myeloproliferative Neoplasms and Myeloid/Lymphoid Neoplasms With Eosinophilia and Tyrosine Kinase Gene Fusions
19. Myelodysplastic Syndromes

SECTION 4 Disorders of Histiocytes, Mast Cells, Plasma Cells, Spleen, and Ancillary Techniques
20. Disorders of Histiocytes
21. Mastocytosis
22. Multiple Myeloma and Other Plasma Cell Neoplasms Pei Lin and Michael Andrew Linden
23. Disorders of the Spleen
24. Flow Cytometric Principles in Hematopathology
25. Molecular Hematopathology

Preface to the Classification of Mature B-, T-, and NK-Cell Leukemias and Lymphomas and the
Classification of Myeloid Neoplasms
The Classification of Mature B-, T-, and Nk-Cell
Leukemias and Lymphomas
The Classification of Myeloid Neoplasms

Book Reviews

"...provide[s] the most important and up-to-date information in hematopathology, for learners at all levels of experience. The book will be useful to anyone learning or practicing hematopathology, including pathology residents, hematopathology fellows, and practicing pathologists who sign out these specimens.... [it] continues to be one of the favorite hematopathology textbooks among pathology trainees and practicing hematopathologists alike. The text is concise yet comprehensive, ideal as a quick reference during sign out. Summary text boxes are excellent and one of the best features of this book. The appendices that compare the two current classification systems are very helpful in navigating this hopefully transitional period in our subspeciality. I highly recommend this book to anyone dealing with hematopathology specimens." Review by Anamarija Perry, MD (University of Michigan Medical School), ©Doody's Review Service, 2025. Doody's Score: 95, 4 Stars!

Review of the previous edition:
"This is a great and much needed update for hematopathology. I would highly recommend it for practicing hematopathologists." -Reviewed by Valerie L. Ng, PhD MD (Alameda County Medical Center/Highland Hospital) Doody's Score: 95, 4 Stars!

Hematopathology,

Editors: By Eric D. Hsi, MD, Sa A. Wang, MD and John R. Goldblum, MD, FCAP, FASCP, FACG

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About the author

Book Reviews

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