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Drug Discovery and Development,

Edition 3 Technology in Transition

Editors: Edited by Raymond G Hill and Duncan Richards

Publication Date: 24 Aug 2021

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Essential insight into drug development and the pharmaceutical industry

With unprecedented interest in the power that the modern therapeutic armamentarium has to combat disease, the new edition of Drug Discovery and Development is an essential resource for anyone interested in understanding how drugs and other therapeutic interventions are discovered and developed, through to clinical research, registration, and market access.

The text has been thoroughly updated, with new information on biopharmaceuticals and vaccines as well as clinical development and target identification. Drug discovery and development continues to evolve rapidly and this new edition reflects important changes in the landscape.

Edited by industry experts Raymond Hill and Duncan Richards, this market-leading text is suitable for undergraduates and graduates undertaking degrees in pharmacy, pharmacology, toxicology, and clinical development through to those embarking on a career in the pharmaceutical industry.

Key Features

Key stages of drug discovery and development

Chapters outline the contribution of individual disciplines to the overall process

Supplemented by specific chapters on different modalities

Includes coverage of Oligonucleotide therapies; cell and gene therapy

Now comes with online access on StudentConsult

About the author

Edited by Raymond G Hill, President, British Pharmacological Society, London, UK and Duncan Richards, Professor Duncan Richards MA DM FRCP FFPM FBPharmacolS, St Hilda’s College,Oxford

Section 1 Introduction and Background

1. Development of the pharmaceutical industry

2. Nature of disease and purpose of therapy

3. Therapeutic modalities

Section 2 Drug Discovery

4. Drug target identification

5. Selecting the modality and planning the project

6. High throughput screening

7. Medicinal Chemistry

8. Biopharmaceuticals and related molecules

9. Emerging modalities: nucleotide based therapy, cell based therapy, gene therapy / Novel and Advanced Process

10. Metabolism and Pharmacokinetical strategies.

11. Role of pharmacology to include pharmacology of newer modalities

12. In vitro in vivo translation

13. Vaccines

Section 3 Drug Development

14. Drug development introduction

15. Drug safety

16. Pharmaceutical development

17. Clinical development

18. Clinical imaging

19. Intellectual property

20. Regulatory affairs

21. Marketing and Patient access to medicines

Section 4 Facts and Figures

22. Facts and Figures; and the Future

ISBN: 9780702078040

Page Count: 384

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