Cellular and Molecular Immunology,

Edition 11

Editors: By Abul K. Abbas, MBBS, Andrew H. Lichtman, MD, PhD, Shiv Pillai, MD, PhD and Sarah Henrickson, MD, PhD

Publication Date: 28 Aug 2025

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Selected for 2025 Doody’s Core Titles® in Immunology

Well-written, readable, and superbly illustrated, Cellular and Molecular Immunology, Eleventh Edition, continues the tradition of excellence established through multiple editions of this bestselling text. Offering an unparalleled introduction to this complex field, it retains a practical, clinical focus while updating and revising all content to ensure clarity and comprehension, bringing readers fully up to date with new and emerging information in this challenging area. It's an ideal resource for medical, graduate, and undergraduate students, as well as a trusted reference for physicians and scientists.

Key Features

Highlights the implications of immunologic science for the management of human disease, emphasizing clinical relevance throughout
Employs a highly accessible writing style that makes difficult concepts easier to understand, and provides clear implications of immunologic science to the management of human disease and clinical practice
Features updates from cover to cover, including new information on COVID-19, genetics and pathogenesis of allergic diseases, newly recognized primary immune regulatory disorders, interactions between the immune system and brain and their role in CNS disorders, and CRISPR/Cas9 based gene editing
Provides a highly visual, full-color description of the key immunologic and molecular processes with a fully updated, comprehensive, and consistent art program, including many new and extensively revised illustrations
Helps readers grasp the details of experimental observations that form the basis for the science of immunology at the molecular, cellular, and whole-organism levels and draw the appropriate conclusions
Includes summary boxes that assist with rapid review and mastery of key material
An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud

About the author

By Abul K. Abbas, MBBS, Emeritus Professor, Department of Pathology, University of California San Francisco, USA; Andrew H. Lichtman, MD, PhD, Professor of Pathology, Brigham and Women's Hospital, Harvard Medical School, USA; Shiv Pillai, MD, PhD, Professor of Medicine and Health Sciences and Technology, Harvard Medical School, Ragon Institute of MGH, MIT and Harvard, USA and Sarah Henrickson, MD, PhD, Assistant Professor, Division of Allergy and Immunology, Department of Pediatrics, Children's Hospital of Philadelphia Department of Pediatrics, Perelman School of Medicine Department of Microbiology, Perelman School of Medicine, USA

1. Overview of the Immune System
2. Cells and Tissues of the Immune System
3. Leukocyte Circulation and Migration Into Tissues
4. Innate Immunity
5. Antibodies and Antigens
6. Antigen Presentation to T Lymphocytes and the Role of Major Histocompatibility Complex Molecules
7. Immune Receptors and Signal Transduction
8. Lymphocyte Development and Antigen Receptor Gene Rearrangement
9. Activation and Regulation of T Lymphocytes
10. Differentiation and Functions of CD4 + Effector T Cells
11. Differentiation and Functions of CD8 + Effector T Cells
12. B-Cell Activation and Antibody Production
13. Effector Mechanisms of Humoral Immunity
14. Specialized Immunity at Epithelial Barriers and in Immune-Privileged Tissues
15. Immunologic Tolerance and Autoimmunity
16. Immunity to Microbes
17. Transplantation Immunology
18. Tumor Immunology
19. Hypersensitivity Disorders
20. Allergy
21. Congenital and Acquired Immunodeficiencies

Book Reviews

Review of the previous edition:
“This is an excellent immunology textbook because it thoroughly dissects the fine developmental process of the immune system. It is well written and this edition’s illustrations are excellent.” --©Doody’s Review Service, 2022, Eric L. Brown, PhD (University of Texas Health Science Center at Houston) Doody’s Score: 92 – 4 Stars!

ISBN: 9780443283581

Page Count: 600

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Medical students, Graduate and undergraduate students of immunology