Murray & Nadel's Textbook of Respiratory Medicine, 2-Volume Set,

Edition 8

Editors: Edited by V. Courtney Broaddus, MD, Nirav R. Bhakta, MD, PhD, Joel D. Ernst, MD, Talmadge E. King Jr, MD, Kathleen F. Sarmiento, MD, Lynn M. Schnapp, MD and Renee D. Stapleton, MD, PhD

Publication Date: 22 Sep 2026

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Covering the entire spectrum of pulmonology in one authoritative point-of-care resource, Murray & Nadel's Textbook of Respiratory Medicine, 8th Edition, remains the go-to clinical guide and training reference for pulmonary physicians, fellows, and other pulmonary practitioners. Edited and authored by pulmonary experts at the top of their field, it offers definitive, well written, full-color coverage of foundational content, basic science, diagnostic strategies, clinical decision-making, and evidence-based treatment, making it highly relevant for both trainees and seasoned clinicians. This edition includes important new chapters and updates, a streamlined and integrated approach to content, and new author teams that bring fresh perspectives to areas like asthma and COPD management, lung cancer molecular biology and targeted therapies, pleural effusions, interstitial lung disease, and outpatient/inpatient ventilator strategies—enhanced with digital tools and online resources for continuous learning and clinical reference.

Key Features

Provides detailed explanations of each disease entity and differential diagnoses with clinical decision-making guidance, evidence-based content, and diagnostic algorithms, authored by global leaders in the field
Reflects the latest advances in respiratory medicine throughout, including diagnostic innovations, breakthrough therapies, and updated clinical guidelines, supporting real-world application and life-long learning
Includes new chapters on medical education, pulse oximetry and capnography, obesity hypoventilation, and both noninvasive and invasive ventilation strategies for chronic respiratory failure, as well as extensively revised content on community-acquired pneumonia, sleep disorders, and critical illness—optimized for clinical practice
Features more than 1,450 anatomic, algorithmic, and radiologic images, including CT/HRCT, MR, and PET, plus extensive online content: 200 procedural and conceptual videos, audio clips of lung sounds, and new instructional videos on bronchoscopy techniques for self-assessment and clinical training
Includes succinct Key Point summaries for each chapter, useful for self-directed learning, self-study exam preparation, and clinical reference
Integrates the scientific foundation and genetics into disease-specific chapters for comprehensive understanding and clinical application
Brings you up to date with the latest respiratory drugs, mechanisms of action, indications, precautions, adverse effects, and clinical guidelines supported by online resources for ongoing education
Sets pulmonary fellows up for success with comprehensive coverage aligned with fellowship curricula—the core knowledge you need to pass your licensing exam and understand the broad range of respiratory medicine for your future career
An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date

About the author

Edited by V. Courtney Broaddus, MD, Professor Emeritus, Division of Pulmonary and Critical Care, University of California, San Francisco, USA; Nirav R. Bhakta, MD, PhD, Associate Professor, Pulmonary, Critical Care, Allergy, and Sleep Medicine, University of California, San Francisco, USA; Joel D. Ernst, MD, Professor and Chief, Division of Experimental Medicine, University of California, San Francisco, USA; Talmadge E. King Jr, MD, Dean, UCSF School of Medicine, Vice Chancellor, Medical Affairs, University of California, San Francisco, USA; Kathleen F. Sarmiento, MD, Professor, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA; Lynn M. Schnapp, MD, George R. and Elaine Love Professor Chair of the Department of Medicine University of Wisconsin School of Medicine and Public Health Madison, WI, USA and Renee D. Stapleton, MD, PhD, Professor of Medicine, Pulmonary and Critical Care Medicine, Larner College of Medicine, University of Vermont, USA

Part 1: Scientific Principles of Pulmonary Medicine
Section A: Anatomy and Development of the Respiratory Tract
1. Anatomy: Structures and Cells
2. Lung Growth and Development
3. Alveolar Compartment
4. Airway Biology
5. Lung Mesenchyme
6. Vascular Biology
7. Lymphatic Biology
8. Stem Cells and Regeneration
Section B: Respiratory Physiology
9. Ventilation, Blood Flow and Gas Exchange
10. Respiratory System Mechanics and Energetics
11. Acid-Base Balance
12. Aerosol and Drug Delivery
13. Control of Breathing and Pathophysiology of Sleep Apnea
14. Pleural Physiology and Pathophysiology
Section C: Defense Mechanisms and Immunology
15. Innate and Adaptive Immunity
16. Microbiome

Part 2: Diagnosis and Evaluation of Respiratory Disease
Section D: Diagnosis
17. History and Physical Examination
18. Microbiologic and Molecular Diagnosis of Lung Infection
19. Thoracic Radiology: Noninvasive Diagnostic Imaging
20. Thoracic Radiology: Image-Guided Invasive Diagnostic and Therapeutic Interventions
21. Pathology
22. Ultrasonography: Principles and Basic Imaging
23. Ultrasonography: Advanced Applications and Procedures (Including POCUS)
24. Positron Emission Tomography
25. Diagnostic Bronchoscopy: Basic Techniques
26. Diagnostic Bronchoscopy: Advanced Techniques (EBUS and navigational)
27. Therapeutic Bronchoscopy: Interventional Techniques
28. Thoracoscopy
29. Thoracic Surgery
Section E: Evaluation
30. Pulmonary Function Testing: Principles
31. Pulmonary Function Testing: Applications
32. Pulse Oximetry and Capnography
33. Exercise Testing
34. Preoperative Evaluation
35. Evaluation of Respiratory Impairment and Disability

Part 3: Clinical Respiratory Medicine
Section F: Evaluation of Common Presentations of Respiratory Disease
36. Dyspnea
37. Cough
38. Chest Pain
39. Wheezing and Stridor
40. Hemoptysis
41. Pulmonary Nodule
42. Aspiration
43. Pulmonary Edema
44. Hypoxemia
45. Hypercapnia
Section G: Infectious Diseases of the Lungs
46. Community-Acquired Pneumonia: General Features
47. Community-Acquired Pneumonia: Specific Pathogens (Including SARS-CoV-2)
48. Influenza
49. Hospital-acquired Pneumonia
50. Ventilator-associated Pneumonia
51. Lung Abscess
52. Tuberculosis: Epidemiology and Prevention
53. Tuberculosis: Pathogenesis and Immunity
54. Tuberculosis: Clinical manifestations and diagnosis
55. Tuberculosis: Treatment of drug-susceptible and drug-resistant
56. Nontuberculous Mycobacterial Infections
57. Fungal Infections: Endemic
58. Fungal Infections: Opportunistic
59. Parasitic Infections
60. Outbreaks, Pandemics, and Bioterrorism
61. Asthma: Pathogenesis and Phenotypes
Section H: Obstructive Diseases
62. Asthma and Obesity
63. Asthma: Diagnosis and Management
64. COPD: Pathogenesis and Natural History
65. COPD: Diagnosis and Management
66. Smoking Hazards: Cigarettes, Vaping, Marijuana
67. Tobacco Use Disorder: Treatment
68. Cystic Fibrosis: Pathogenesis and Epidemiology
69. Cystic Fibrosis: Diagnosis and Management
70. Bronchiectasis
71. Upper Airway Disorders
72. Large Airway Disorders
73. Bronchiolitis
Section I: Neoplasms of the Lungs
74. Lung Cancer: Molecular Biology and Targets
75. Lung Cancer: Epidemiology
76. Lung Cancer: Screening
77. Lung Cancer: Diagnosis and Staging
78. Lung Cancer: Treatment
79. Rare Primary Lung Tumors
80. Metastatic Malignant Tumors
81. Benign Lung Tumors
Section J: Disorders of Pulmonary Circulation
82. Pulmonary Thromboembolism: Presentation and Diagnosis
83. Pulmonary Thromboembolism: Prophylaxis and treatment
84. Pulmonary Hypertension: General Approach
85. Pulmonary Arterial Hypertension: Group 1
86. Pulmonary Hypertension due to Lung Disease: Group 3
87. Pulmonary Hypertension due to Chronic Thromboembolic Disease: Group 4
88. Pulmonary Vasculitis
89. Pulmonary Vascular Anomalies
Section K: Infiltrative and Interstitial Lung Diseases
90. Idiopathic Pulmonary Fibrosis (including Interstitial Lung Abnormalities)
91. Nonspecific Interstitial Pneumonitis and other Idiopathic Interstitial Pneumonias
92. Hypersensitivity Pneumonitis
93. Connective Tissue Diseases
94. Sarcoidosis
95. Diffuse Alveolar Hemorrhage
96. Pulmonary Langerhans Cell Histiocytosis and Rare Infiltrative Diseases
97. Eosinophilic Lung Diseases
98. Lymphangioleiomyomatosis and Other Cystic Lung Disease
99. Pulmonary Alveolar Proteinosis Syndrome
100. Drug-induced Pulmonary Disease
101. Asthma in the Workplace
102. Pneumoconioses
103. Indoor and Outdoor Air Pollution
104. Acute Pulmonary Responses to Toxic Exposures
105. Trauma and Blast Injuries
106. High Altitude
107. Air Travel
108. Diving Medicine
Section M: Disorders of the Pleura
109. Pleural Effusion
110. Pleural Infections
111. Pneumothorax
112. Chylothorax
113. Pleural Fibrosis and Non-Expandable Lung
114. Hemothorax
115. Pleural Malignancy
Section N: Disorders of the Mediastinum
116. Mediastinal Tumors and Cysts
117. Mediastinitis and Fibrosing Mediastinitis
Section O: Respiratory Manifestations of Extrapulmonary Disorders
118. Pulmonary Complications of HIV Infection
119. Pulmonary Complications of Primary Immunodeficiencies (and Immunotherapies)
120. Pulmonary Complications of Stem Cell and Solid Organ Transplantation
121. Pulmonary Complications of Abdominal Diseases
122. Pulmonary Complications of Hematologic Diseases
123. Pulmonary Complications of Endocrine Diseases
124. The Lung in Obstetric and Gynecologic Diseases
125. The Respiratory System and Neuromuscular Diseases
126. The Respiratory System and Chest Wall Diseases
Section P: Disorders of Sleep and Control of Breathing
127. Consequences of Sleep Disruption
128. Sleep-disordered Breathing: General Approach
129. Obstructive Sleep Apnea
130. Central Sleep Apnea
131. Obesity Hypoventilation
132. Sleep-disordered Breathing: Treatment
Section Q: Management of Respiratory Failure
133. Acute Ventilatory Failure
134. Acute Respiratory Distress Syndrome
135. Mechanical Ventilation
136. Noninvasive Ventilation for Acute Respiratory Failure
137. Noninvasive and Invasive Ventilation for Chronic Respiratory Failure
138. Noninvasive Support of Oxygenation
139. Extracorporeal Support of Gas Exchange
140. Pulmonary Rehabilitation
141. Lung Transplantation
142. End-of-life Care in Respiratory Failure
Section R: Education
143. Medical Education in Pulmonary and Critical Care Medicine

ISBN: 9780443249730

Page Count: 2272

Illustrations : Illustrated

Retail Price :

Murray & Nadel's Textbook of Respiratory Medicine, 2-Volume Set,

Editors: Edited by V. Courtney Broaddus, MD, Nirav R. Bhakta, MD, PhD, Joel D. Ernst, MD, Talmadge E. King Jr, MD, Kathleen F. Sarmiento, MD, Lynn M. Schnapp, MD and Renee D. Stapleton, MD, PhD

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About the author