Obstetric Imaging: Fetal Diagnosis and Care,

Edition 3

Editors: Edited by Joshua A. Copel, MD

Publication Date: 18 Jun 2025

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Written and edited by internationally recognized maternal-fetal imaging experts, Obstetric Imaging: Fetal Diagnosis and Care, Third Edition, provides up-to-date, authoritative guidelines for more than 200 obstetric conditions and procedures, keeping you at the forefront of this fast-changing field. You’ll find comprehensive coverage of basic and advanced techniques, normal and abnormal findings, new technologies, and all available modalities. Highly regarded by both practitioners and trainees, it’s an ideal resource for maternal-fetal medicine specialists, obstetricians, radiologists, midwives, nurse practitioners and sonographers.

Key Features

Covers the extensive and ongoing advances in maternal and fetal imaging in a highly templated, bulleted format for quicker access to common and uncommon findings
Provides detailed, expert guidance on optimizing diagnostic accuracy from ultrasound, 3D ultrasound, Doppler, MRI, elastography, image-guided interventions, and more
Contains new chapters on amyoplasia/arthrogryposis; maternal structures including the cervix, fibroids, and ovarian and other adnexal masses; complications due to COVID-19; and artificial intelligence approaches in obstetric imaging
Offers new and updated coverage of the genetic basis of fetal diseases, as well as new diagnoses and management protocols, expanded differential diagnoses, and updated guidelines and practice standards
Features nearly 1,500 images, including 400 in full color, and 150+ videos that demonstrate imaging techniques as well as guidance on interpreting results
Provides differential imaging approaches and interpretation guidelines with extensive comparative image panels that represent every modality and every type of obstetric imaging
Includes must-know information in easy-to-spot boxes: Classic Signs, What the Referring Physician Needs to Know, and Key Points that offer expert tips from top experts in the field
An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date

About the author

Edited by Joshua A. Copel, MD, Professor and Vice Chair, Obstetrics, Obstetrics, Gynecology, and Reproductive Sciences, Professor, Pediatrics, Yale University School of Medicine, New Haven, CT, USA

PART 1 Atlas of Selected Normal Images
1. Atlas of Selected Normal Images

PART 2 First-Trimester Complications
2. Pregnancy of Unknown Location, Early Pregnancy Loss, Ectopic Pregnancy, and Cesarean Scar Pregnancy
3. The First-Trimester Fetal Anatomy Scan
4. Nuchal Translucency

PART 3 Head and Neck
SECTION ONE Central Nervous System
5. Choroid Plexus Anomalies: Cysts and Papillomas
6. Corpus Callosum and Septum Pellucidum Anomalies
7. Cortical Development and Disorders
8. Cerebellar Anomalies
9. Holoprosencephaly
10. Intracranial Hemorrhage, Cysts, Tumors, and Destructive Lesions
11. Neural Tube Defects: Acrania-Exencephaly-Anencephaly Sequence, Cephalocele, Craniorachischisis, and Spinal Dysraphism
12. Vascular Cerebral Anomalies
13. Ventriculomegaly

SECTION TWO Facial Anomalies
14. Facial Dysmorphism
15. Cleft Lip and Palate
16. Hypertelorism and Hypotelorism
17. Micrognathia and Retrognathia
18. Choanal Atresia

SECTION THREE Neck Anomalies
19. Cystic Hygroma
20. Neck Teratoma
21. Fetal Thyroid Masses and Fetal Goiter
22. Congenital High Airway Obstruction Syndrome and Bronchial Atresia

PART 4 Thorax
23. Congenital Pulmonary Airway Malformation
24. Bronchopulmonary Sequestration
25. Hydrothorax
26. Scimitar Syndrome
27. Thymus
28. Other Thoracic Tumors and Masses

PART 5 Heart and Great Vessels
SECTION ONE Normal Heart
29. Normal Fetal Heart

SECTION TWO Septal Defects
30. Ventricular Septal Defect
31. Atrioventricular Septal Defect

SECTION THREE Right Heart Defects
32. Tricuspid Atresia
33. Ebstein Anomaly and Tricuspid Dysplasia
34. Pulmonary Stenosis and Atresia

SECTION FOUR Left Heart Defects
35. Aortic Stenosis and Aortic Atresia
36. Hypoplastic Left Heart, Mitral Atresia
37. Aortic Coarctation
38. Interruption of the Aortic Arch
39. Aortic Arch Anomalies

SECTION FIVE Conotruncal Anomalies
40. Tetralogy of Fallot
41. Complete Transposition of Great Arteries
42. Double-Outlet Right Ventricle
43. Common Arterial Trunk

SECTION SIX Other Anomalies
44. Double-Inlet Single Ventricle
45. Atrial Isomerism
46. Anomalies of the Pulmonary Venous Return
47. Anomalies of the Systemic Venous Return
48. Cardiomyopathy
49. Cardiac Tumors

SECTION SEVEN Arrhythmias
50. Arrhythmias

PART 6 Abdomen and Pelvis
51. Gastroschisis
52. Omphalocele
53. Echogenic Bowel
54. Congenital Diaphragmatic Hernia
55. Intestinal Obstruction
56. Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome
57. Abdominal Cysts
58. Intraabdominal Masses
59. Hepatic Anomalies
60. Fetal Hepatic Calcification
61. Biliary Anomalies
62. Fetal Spleen
63. Abnormal Kidney Location
64. Abnormal Kidney Size
65. Unilateral Renal Agenesis
66. Bilateral Renal Agenesis
67. Renal Pelvis Dilatation
68. Duplicated Collecting System
69. Posterior Urethral Valves
70. Multicystic Dysplastic Kidney
71. Autosomal Recessive (Infantile) Polycystic Kidney Disease
72. Fetal Adrenal Abnormalities
73. Ambiguous Genitalia
74. Cloacal Abnormalities
75. Sacrococcygeal Teratoma and Fetus in Fetu

PART 7 Skeletal Dysplasias: An Overview
SECTION ONE Osteochondrodyplasias
76. Atelosteogenesis Disorders
77. Campomelic Dysplasia
78. Chondrodysplasia Punctata
79. Diastrophic Dysplasia Sulfate Transporter (DTDST) (Including AOII and Achondrogenesis IB)
80. Fibroblast Growth Factor Receptor 3 (FGFR3) Disorders: Thanatophoric Dysplasia, Achondroplasia, and Hypochondroplasia
81. Hypophosphatasia
82. Osteogenesis Imperfecta
83. Radial Ray Deficiency (Limb Deficiency)
84. Russell-Silver Syndrome
85. Skeletal Ciliopathies (Short-Rib Polydactyly Syndromes)
86. Spondyloepiphyseal Dysplasia Congenita
87. Other Type II Collagen Disorders

SECTION TWO Findings—Spinal Defects
88. Caudal Regression Syndrome
89. Spinal Abnormalities and Klippel-Feil Syndrome

SECTION THREE Findings—Anomalous Digits
90. Abnormal Hands: Focus on the Thumbs

SECTION FOUR Findings—Other
91. Craniosynostosis
92. Arthrogryposis/Amyoplasia
93. Clubfoot (Talipes Equinovarus)

PART 8 Maternal Reproductive Structures, Placenta, and Fluid
95. Cervical Length and Spontaneous Preterm Birth
96. Fibroids in Pregnancy
97. Ovarian and Other Adnexal Masses in Pregnancy
98. Placental Abruption
99. Placenta Accreta
100. Amniotic Band Sequence
101. Chorioangioma
102. Choriocarcinoma
103. Placenta Circumvallate
104. Cord Cyst
105. Cord Varix
106. Gestational Trophoblastic Disease
107. Limb-Body Wall Complex
108. Placenta Previa
109. Vasa Previa
110. Polyhydramnios
111. Oligohydramnios

PART 9 Multiple Gestation
112. Chorionicity of Multiple Gestations
113. Monochorionic Monoamniotic Twin Gestations
114. Monochorionic Diamniotic Twin Gestations
115. Dichorionic Diamniotic Twin Gestations
116. Twin-Twin Transfusion Syndrome
117. Twin Reversed Arterial Perfusion Sequence
118. Diagnostic Procedures in Multiples

PART 10 Fetal Growth
119. Fetal Macrosomia and Overgrowth Syndromes
120. Fetal Growth Restriction

PART 11 Chromosomes
SECTION ONE Aneuploidies
121. Prenatal Genetic Testing: A Pragmatic Approach
122. Introduction to Aneuploidy and Other Cytogenetic Abnormalities
123. Triploidy
124. Trisomy 13
125. Trisomy 18
126. Trisomy 21
127. Turner Syndrome (Monosomy X)
128. Mosaic Trisomies 8, 9, and 16

SECTION TWO Deletion Syndromes
129. 22q11.2 Deletion Syndrome
130. Chromosome 4p Deletion Syndrome (Wolf-Hirschhorn Syndrome)
131. Chromosome 5p Deletion Syndrome (Cri du Chat Syndrome)
132. Miller-Dieker Syndrome (17p13.3 Deletion Syndrome)

PART 12 Syndromes
SECTION ONE Mendelian and Multisystem Genetic Disorders
133. CHARGE Syndrome
134. Cornelia de Lange Syndrome
135. Fraser Syndrome
136. Fryns Syndrome
137. Goldenhar Syndrome
138. Klippel-Trénaunay-Weber Syndrome
139. Holt-Oram Syndrome
140. Meckel-Gruber Syndrome
141. Neu-Laxova Syndrome
142. Noonan Syndrome
143. Pentalogy of Cantrell
144. Pierre Robin Sequence
145. Poland Sequence
146. Prune-Belly Syndrome
147. Roberts Syndrome
148. Cystic Fibrosis
149. Pontocerebellar Disorders
150. Tuberous Sclerosis
151. Sirenomelia
152. Smith-Lemli-Opitz Syndrome
153. VACTERL Association

SECTION TWO Fetal Fluid Collections
154. Lymphedema and Lymphatic Malformations
155. Nonimmune Hydrops Fetalis
156. Immune Hydrops Fetalis

PART 13 Infections
157. Cytomegalovirus, Rubella, Toxoplasmosis, Herpes Simplex Virus, and Varicella
158. Congenital Zika Virus Syndrome
159. Parvovirus B19 Infection During Pregnancy
160. Congenital Syphilis
161. Coronavirus Disease 2019

PART 14 Fetal Assessment
162. Doppler Ultrasound Evaluation of the Fetus and Placenta
163. Doppler Ultrasound of the Uterine Artery
164. The Middle Cerebral Artery Doppler
165. Precordial Venous System
166. Fetal Biophysical Profile

PART 15 Procedures
167. Amniocentesis
168. Cordocentesis and Fetal Transfusion
169. Chorionic Villus Sampling
170. Radiofrequency Ablation
171. Fetoscopic Laser Surgery
172. Fetal Shunts
173. Multifetal Pregnancy Reduction
174. Open and Endoscopic Fetal Surgery

PART 16 Technology and New Ultrasound Applications
175. Ultrasound Physics for the Clinician
176. Elasticity Imaging in Obstetrics
177. Artificial Intelligence Approaches in Obstetric Imaging
178. Magnetic Resonance Imaging in Obstetrics
179. Three-Dimensional Ultrasound: Techniques and Clinical Applications
180. Intrapartum Ultrasound to Determine Birth Progress

Book Reviews

Review of the previous edition:
"I am impressed by this book … Every obstetric imaging department should have access to it." -2018 BMA Awards: Highly Commended, Radiology

"This is an excellent book and one that should be on the shelf in every maternal-fetal medicine office. It is comprehensive yet easy to read. Chapters are well thought out and organized by disorder, making it easy to locate the topic of interest." -Reviewed by Anthony Shanks, MD (Indiana University School of Medicine) Doody's Score: 97, 5 Stars!

Obstetric Imaging: Fetal Diagnosis and Care,

Editors: Edited by Joshua A. Copel, MD

Description

Key Features

About the author

Book Reviews